Nowadays, people are getting more health contois and living a balanced healthy lifestyle. Some of them still unsure why their cholesterol level is high although they are practising a healthy lifestyle. Some may even blame genetics for the high cholesterol level. This article will explain better about the high cholesterol in a certain group of people.
Polygenic familial hypercholesterolemia is one of the common genetic hyperlipidemias. It is diagnosed based on 2 or more family members having LDL cholesterol levels above the 90th percentile without any tendon xanthomas. Tendon xanthomas are papules and nodules usually found in the tendons of the hands, feet, and heel. Familial hypercholesterolemia is another type of disorder, where the LDL receptor gene is defected, characterized by elevated cholesterol since birth. It was suggested to be screened at the optimum age range from 2 to 10 years old.
It is important to highlight that there is no sufficient evidence to support dietary cholesterol in developing cardiovascular diseases. Thus, the recommendation of restricting dietary cholesterol to 300mg/day was removed from American Dietary Guideline. Total fat includes saturated fat intake should be concerned as increased saturated intake related to increased risk of cardiovascular disease. Avoiding high-fat food helps in preventing the development of high cholesterol.
Someone may experience that his/her cholesterol still remains high even they had tried so hard in cutting down the fat intake.
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Conclusion:
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References:
1. Clinical Practice Guidelines. (2017). Management of Dyslipidemia (5th ed.). Ministry of Health.
2. Gulati, S., Misra, A., & Pandey, R. M. (2017). Effects of 3 g of soluble fiber from oats on lipid levels of Asian Indians-a randomized controlled, parallel arm study. Lipids in health and disease, 16(1), 71.
3. Mahan, L. K., Escott-Stump, S., Raymond, J. L., & Krause, M. V. (2016). Krause's food & the nutrition care process (14th ed.). Elsevier Health Sciences.
4. Nordestgaard M, et al: Familial hypercholesterolemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society, Eur Heart J 34:3478, 2013.
5. Soliman, G. (2018). Dietary cholesterol and the lack of evidence in cardiovascular disease. Nutrients, 10(6), 780.
Written by,
Venus Chey, BSc Dietetics (UPM), MJ Health Care Centre